But she should have known better, too

She was a faithful member of Christ the King Church. Her friends were legion from the period of her elementary school in North Bay to those she made at D. N. Penetrances can be calculated directly from genotype counts in a case control study using Bayes rule, P(D) is disease prevalence, and P(AA) is the population frequency of genotype AA. P(AA) is estimated from control genotype frequency if controls are a random population sample of people, or if the disease is rare. If controls are selected to be unaffected and the disease is common, then P(AA) is determined from the weighted case and control frequencies.Alternatively, the summary measures of risk presented in meta analysis of genetic association studies may be used to estimate penetrances, enabling risk calculations to be based on more robust estimates than a single case control study.

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